Mitochondrial Targeted Antioxidant Peptide
Disclaimer: This product is for laboratory research purposes only. Not for human consumption.
Standardized handling, dosing, and storage guidelines for SS-31 in bioenergetic and mitochondrial research applications.
SS-31 (Elamipretide) is a novel, mitochondria-targeted peptide that selectively binds to cardiolipin on the inner mitochondrial membrane. By stabilizing cardiolipin, it restores mitochondrial bioenergetics, enhances ATP production, and reduces the leakage of reactive oxygen species (ROS). It is heavily researched for its potential in treating ischemia-reperfusion injury, neurodegenerative diseases, and age-related metabolic decline.
Initial reduction in mitochondrial ROS production and stabilization of inner membrane potential.
| Compound | Primary Mechanism | Key Benefit | Admin. |
|---|---|---|---|
| SS-31 | Cardiolipin Binding | ATP & ROS balance | SubQ |
| MOTS-c | Mitochondrial Derived Peptide | Metabolic homeostasis | SubQ |
| Humanin | Mitochondrial Derived Peptide | Cytoprotection | SubQ |
| Glutathione | Systemic Antioxidant | General ROS scavenging | IV/SubQ |
SS-31 acts directly on the inner mitochondrial membrane, optimizing the electron transport chain to maximize energy output while minimizing damaging oxidative stress.
Selectively targets and binds to cardiolipin on the inner mitochondrial membrane, stabilizing its structure.
Prevents the leakage of electrons from the electron transport chain, drastically reducing reactive oxygen species.
Restores optimal electron transport and oxidative phosphorylation, maximizing cellular ATP production.
Relatively short plasma half-life, but exhibits prolonged accumulation and action within mitochondria.
High via subcutaneous injection. Penetrates cell membranes and localizes to mitochondria rapidly.
Cleared primarily via renal excretion without significant hepatic metabolism.
Cardiolipin (inner mitochondrial membrane).
SS-31 is highly valued in research for its ability to rescue mitochondrial function under severe stress.
Explores the mechanism by which SS-31 stabilizes the inner mitochondrial membrane.
CARDIOLOGYA review of SS-31's efficacy in protecting cardiac tissue during ischemic events.
NEUROLOGYInvestigates the role of mitochondrial antioxidants in slowing cognitive decline.
Explore research-use products associated with this compound profile, including available formats, related blends, and supporting lab documentation where available.
Explore supporting tools, protocol references, and batch documentation to help navigate research-use product information.
Review reference-oriented handling, preparation, and storage notes for laboratory research workflows.
View protocolsUse our research calculator for reference preparation workflows and lab-focused planning support.
Open calculatorAccess available batch documentation, lab testing references, and certificates of analysis where available.
View COAsDeeper research-focused questions about SS-31, elamipretide, Szeto-Schiller peptide research, mitochondrial targeting, cardiolipin binding, inner mitochondrial membrane biology, oxidative stress models, storage, and batch documentation.
SS-31, also known as elamipretide, MTP-131, or Bendavia in research literature, is a mitochondria-targeted tetrapeptide commonly discussed in cardiolipin, inner mitochondrial membrane, oxidative stress, and mitochondrial bioenergetics research. In laboratory contexts, SS-31 is often studied around mitochondrial membrane structure, electron transport chain models, reactive oxygen species endpoints, ATP-linked metabolism, and cardiolipin-associated pathway biology. On this site, SS-31 is positioned strictly as a laboratory research reference compound.
SS-31 refers to Szeto-Schiller peptide 31, a member of the Szeto-Schiller mitochondrial-targeted peptide research class. The compound is also commonly referred to as elamipretide in pharmaceutical and clinical research contexts. For SEO clarity, an SS-31 page should include the terms SS-31, elamipretide, Szeto-Schiller peptide, MTP-131, and Bendavia where appropriate because researchers may search using different names.
Yes. SS-31 is commonly described as a tetrapeptide, meaning it is built from a four-residue peptide structure. It is different from many catalog peptides because its main research identity is mitochondrial targeting and cardiolipin-associated membrane biology rather than tissue repair, melanocortin signaling, growth hormone secretagogue activity, or metabolic receptor agonism.
Elamipretide is the pharmaceutical and clinical research name commonly associated with SS-31. In scientific literature, elamipretide is discussed as a mitochondria-targeted peptide that interacts with cardiolipin on the inner mitochondrial membrane. A research-use SS-31 page can mention elamipretide as a synonym, but it should not imply that a research-use product is equivalent to a regulated prescription medication or approved clinical product.
SS-31 is commonly discussed in relation to cardiolipin, a phospholipid found in the inner mitochondrial membrane that is important for mitochondrial structure and electron transport chain organization. In research models, the SS-31 and cardiolipin relationship is used to study mitochondrial membrane stability, cristae structure, oxidative stress response, electron transport efficiency, and bioenergetic pathway signaling.
Cardiolipin is important in mitochondrial research because it helps support inner mitochondrial membrane architecture, cristae organization, and the function of electron transport chain complexes. Since mitochondrial bioenergetics depends heavily on inner membrane organization, cardiolipin is a major pathway term for SS-31 education. This makes cardiolipin one of the strongest scientific and SEO anchors for an SS-31 resource page.
SS-31 is studied in mitochondrial dysfunction research because mitochondrial membrane organization, cardiolipin integrity, oxidative stress, and electron transport chain performance are closely connected in cellular energy models. Research discussions may examine how SS-31 relates to mitochondrial membrane potential, reactive oxygen species endpoints, ATP-linked metabolism, cytochrome c interactions, and cellular stress-response models.
SS-31 is often discussed in oxidative stress research because mitochondrial dysfunction can increase reactive oxygen species production and disturb redox balance. In SS-31 research models, oxidative stress endpoints may include reactive oxygen species markers, mitochondrial membrane potential, lipid peroxidation markers, electron transport chain activity, ATP-linked metabolism, and cell-stress signaling. Page copy should frame this as laboratory pathway research, not as a wellness or anti-aging claim.
SS-31 and MOTS-c are both commonly discussed in mitochondrial research, but they represent different categories. SS-31 is typically positioned around cardiolipin, inner mitochondrial membrane biology, and mitochondrial-targeted peptide research. MOTS-c is usually discussed as a mitochondrial-derived peptide connected to AMPK signaling, metabolic adaptation, and cellular stress-response research. They may sit near each other in a mitochondrial research catalog, but they should have separate resource pages because the mechanisms and SEO intent are different.
SS-31, NAD+, and Glutathione can all appear in mitochondrial or cellular stress research, but they are not the same type of compound. SS-31 is a mitochondria-targeted tetrapeptide commonly discussed around cardiolipin and inner mitochondrial membrane biology. NAD+ is a dinucleotide coenzyme involved in NAD+/NADH redox metabolism and NAD+-dependent enzymes. Glutathione is a tripeptide thiol involved in GSH/GSSG redox cycling and oxidative stress pathway research.
SS-31 is the research name commonly associated with elamipretide, while Forzinity is a regulated prescription product containing elamipretide injection. A research-use SS-31 product should not be confused with Forzinity, any approved medication, or any clinical protocol. This page uses SS-31 and elamipretide terminology for scientific reference only and does not imply that research-use material is clinically interchangeable with a regulated drug product.
SS-31 should not be presented on this page as a dietary supplement, wellness product, mitochondrial treatment, anti-aging product, performance product, or self-administered compound. Although elamipretide has a regulated prescription-drug context, research-use SS-31 material sold by Symbiotic Pharmaceuticals should not be confused with any approved medication, prescription product, clinical protocol, or consumer health product. This page is written only for educational reference and laboratory research positioning.
SS-31 is commonly associated with research areas involving cardiolipin biology, inner mitochondrial membrane structure, mitochondrial bioenergetics, electron transport chain models, oxidative stress endpoints, reactive oxygen species signaling, mitochondrial membrane potential, cristae organization, cytochrome c interactions, ATP-linked metabolism, and mitochondrial dysfunction models. It is best positioned as a mitochondrial-targeted peptide research compound rather than a repair peptide, growth hormone secretagogue, melanocortin compound, or metabolic receptor agonist.
SS-31 research discussions may involve endpoints related to cardiolipin interaction, mitochondrial membrane potential, electron transport chain activity, ATP-linked metabolism, reactive oxygen species markers, lipid peroxidation markers, cytochrome c behavior, mitochondrial respiration, cristae structure, oxidative stress response, and cellular stress signaling. The exact endpoints depend on the research model, analytical method, tissue system, and whether the focus is mitochondrial membrane biology, bioenergetics, or oxidative stress response.
Storage requirements can vary by product format, batch, and label instructions. For research handling, follow the product label and applicable laboratory storage standards. In general, research peptides should be protected from unnecessary heat, light, moisture, contamination, oxidation, and repeated temperature changes because these conditions may affect long-term stability and handling quality.
Available certificates of analysis and batch documentation can be reviewed through the Lab Results / COA page. Documentation availability may vary by product and inventory lot. Where available, batch documentation may include product identification, purity-focused testing references, assay references where applicable, and supporting analytical documentation.
Yes. SS-31 products listed on Symbiotic Pharmaceuticals are intended for laboratory research and analytical reference use only. They are not intended for human consumption, animal consumption, diagnostic use, therapeutic use, mitochondrial disease treatment, anti-aging use, wellness use, performance use, injection use, or self-administration. Any discussion on this page is provided for educational and research-reference purposes only.
The information provided in this resource hub is for educational and informational purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease.